Israel Friday launched a massive attack on Gaza amid Iran's threat to avenge a strike in Syria this month that killed two Iranian generals.

As ceasefire talks aiming to pause the six-month-old war dragged on, Iran has threatened to launch an attack on Israel spurring India, the US, and France to recommend its citizens avoid travelling to the region.

According to reports, Israel dropped missiles and shells throughout the night.

Israel last week pulled its troops from the devastated city of Khan Yunis after months of fighting.

However, officials said they were preparing for operations against Hamas operatives in Rafah, near the Egyptian border.

Authorities in the Hamas-ruled coastal Palestinian territory on Friday reported dozens of new air strikes in Gaza's central region.

The Hamas media office said 25 people were taken to hospital in Deir al-Balah city "as a result of an air strike on a house of the al-Tabatibi family."